Cetirizine is a non-sedating antihistamine that works by blocking histamine (H-1) receptors on cells. It is similar to the other second generation antihistamines loratadine ( Claritin ), fexofenadine ( Allegra ) and azelastine ( Astelin ). Histamine is a chemical that is responsible for many of the signs and symptoms of allergic reactions, for example, swelling of the lining of the nose, sneezing , and itchy eyes. Histamine is released from histamine-storing cells (mast cells) and then attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cells to be "activated," releasing other chemicals that produce the effects that we associate with allergy , for example, sneezing . Certirizine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation of H1 receptor-containing cells by histamine. Unlike the first generation antihistamines, cetirizine and other second-generation antihistamines do not readily enter the brain from the blood, and, therefore, they cause less drowsiness. Cetirizine may cause more drowsiness than other second generation antihistamines. The FDA approved cetirizine in September 1996.
Deliveries , since we ship from a western countries inside the EU we never have problems with shipping within the EU. For other countries we have developed a style of shipping that is very successful to pass through the customs. For this reason your products might arrive without correct labels, but the original label will arrive later in a simple letter. The invoice of the order might look like something else, please ignore.