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Princeton Brain & Spine surgeon Mark R. McLaughlin, MD, FACS, FAANS trained with Peter Jannetta, ., the "father" of modern microvascular decompression surgery for trigeminal neuralgia, hemifacial spasm, glossopharyngeal neuralgia, and other cranial nerve rhizopathies. Dr. McLaughlin worked closely with Dr. Jannetta in the ongoing research, and was the lead author of the paper "Microvascular decompression of cranial nerves: lessons learned after 4400 operations" published in the Journal of Neurosurgery in January 1999. On PUBMED
Various locations were proposed for the primary lesion during the nineteenth century, including nerve roots , ganglia , trunks and branches, as well as the brain and spinal cord. In 1828, JC Warren  and TJ Graham  placed the cause in the trunk or branch of the nerve innervating the perceived site of the pain, though Graham also attributed neuralgia to "morbid sensibility of the nervous system" due to "great disorder of the general health". Teale in 1830  and many after him argued that it may be located in the spinal cord or nerve root. Later in the century some proposed it may be an affliction of organs such as the uterus or liver, while others classed certain headaches as neuralgias, and proposed that emotional distress may promote the condition.