A branched chain amino acid (BCAA) product might not hurt during your off-cycle time either, as recovery may be slowed compared to what you were used to on-cycle. It should help you recover faster and get more out of your workouts. A fish oil supplement might also be a good idea to help balance your lipid and triglyceride levels, which remember were likely altered for the negative during your steroid cycles. Off-cycle may also be a good time to invest in some of the other general health promoting vitamins and herbs etc. that may be fond of taking. The bottom line is, your off time is supposed to be “off time” for a reason. This is the time to let your body get back to its natural state of hormonal balance, and for you to enjoy a period where you are not using steroids and perhaps placing certain strains on your health. Take advantage of this time and use it for what its worth – keeping you healthy and happy.
Protein S can bind to negatively charged phospholipids via the carboxylated Gla domain. This property allows Protein S to function in the removal of cells which are undergoing apoptosis . Apoptosis is a form of cell death that is used by the body to remove unwanted or damaged cells from tissues. Cells, which are apoptotic (. in the process of apoptosis ), no longer actively manage the distribution of phospholipids in their outer membrane and hence begin to display negatively charged phospholipids, such as phosphatidyl serine, on the cell surface. In healthy cells, an ATP ( Adenosine triphosphate )-dependent enzyme removes these from the outer leaflet of the cell membrane. These negatively charged phospholipids are recognized by phagocytes such as macrophages . Protein S can bind to the negatively charged phospholipids and function as a bridging molecule between the apoptotic cell and the phagocyte. The bridging property of Protein S enhances the phagocytosis of the apoptotic cell, allowing it to be removed 'cleanly' without any symptoms of tissue damage such as inflammation occurring.
When concluding a cycle, some steroid users also follow a practice of first slowly reducing their dosages (tapering). This tapering may proceed for a 3-4 week period, and will involve an even stepping down of the dose each week until the point of drug discontinuance. It is unknown, however, if such tapering offers any tangible value. This practice has never been evaluated in a clinical setting, and is not widely recommended with steroid medications as it is with some other drugs such as thyroid hormones or antidepressants. Virtually every high-dose AAS administration study can also be found to end at the maximum dosage, with no time allotted to tapering. One flaw in the logic of using a tapering program is that they are ostensibly designed to aid hormone recovery. Recovery is not possible, however, while supraphysiological levels of androgens are present, and such levels are usually found during all weeks of a normal (nonmedical) steroid taper. Individuals remain cautioned that dosage tapering is not a proven way to reduce post- cycle muscle catabolism.