Behçet's disease is a triad of mouth ulcers, genital ulcers and anterior uveitis .  The main feature of Behçet's disease is aphthous-like ulceration, but this is usually more severe than seen in aphthous stomatitis without a systemic cause, and typically resembles major or herpetiforme ulceration or both.   Aphthous-like ulceration is the first sign of the disease in 25–75% of cases.  Behçet's is more common in individuals whose ethnic origin is from regions along the Silk Road (between the Mediterranean and the Far East ).  It tends to be rare in other countries such as the United States and the United Kingdom.  MAGIC syndrome is a possible variant of Behçet disease, and is associated with aphthous-like ulceration. The name stands for "mouth and genital ulcers with inflamed cartilage" ( relapsing polychondritis ). 
Dogs suffering from IBD may demonstrate such signs as chronic or recurring vomiting, loose stools, loss of appetite, lethargy, low-grade fever, poor-quality hair coat and weight loss—signs that can be present in other medical conditions, making diagnosing IBD trickier. These dogs typically have inflammation of the stomach lining, colon and small intestine. Their immune systems are waging war on the invasion of bacterial, food or parasitic antigens. They are miserable and in pain, and their owners are often frustrated by the lack of a quick diagnosis and recovery.