Vesicle-mediated steroid hormone secretion in drosophila melanogaster

Protein S can bind to negatively charged phospholipids via the carboxylated Gla domain. This property allows Protein S to function in the removal of cells which are undergoing apoptosis . Apoptosis is a form of cell death that is used by the body to remove unwanted or damaged cells from tissues. Cells, which are apoptotic (. in the process of apoptosis ), no longer actively manage the distribution of phospholipids in their outer membrane and hence begin to display negatively charged phospholipids, such as phosphatidyl serine, on the cell surface. In healthy cells, an ATP ( Adenosine triphosphate )-dependent enzyme removes these from the outer leaflet of the cell membrane. These negatively charged phospholipids are recognized by phagocytes such as macrophages . Protein S can bind to the negatively charged phospholipids and function as a bridging molecule between the apoptotic cell and the phagocyte. The bridging property of Protein S enhances the phagocytosis of the apoptotic cell, allowing it to be removed 'cleanly' without any symptoms of tissue damage such as inflammation occurring.

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Kit Specifications Binding Capacity Per Column Up to 50 μg RNA Maximum Loading Volume Per Spin Column 650 μL Size of RNA Purified All sizes, including < 200 nt Time to Complete 10 Purifications 20 minutes Maximum Amount of Starting Material Liver (10 mg) 30 µg Kidney (10 mg) 10 µg Brain (10 mg) 12 µg Blood (hamster, 100µL 5 µg HeLa (1 x 10 6 ) 15 µg CHO (1 x 10 6 ) 11 µg Yeast (1 x 10 8 ) 30 µg E. coli (1 x 10 9 ) 43 µg Storage Conditions and Product Stability
All solutions should be kept tightly sealed and stored at room temperature. These reagents should remain stable for at least 1 year in their unopened containers.

Vesicle-mediated steroid hormone secretion in drosophila melanogaster

vesicle-mediated steroid hormone secretion in drosophila melanogaster

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vesicle-mediated steroid hormone secretion in drosophila melanogaster

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